 Sen. Joe Manchin III (D-W.Va.), a key holdout vote on President Biden's domestic agenda, on Wednesday. (Andrew Harnik/AP) Disputes over the long-elusive package to overhaul the nation's health care, education, climate and tax laws stem in large part from the two moderate holdouts in the Senate, but Democratic leaders say they are closer to finalizing the initiative, which some lawmakers believe will cost about $1.75 trillion over 10 years. By Tony Romm and Mike DeBonis ● Read more » | 
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